Cleveland, OH
September 5-6, 2025

Bike to Cure Registration is Open!

Who will you ride for?

Register Today!

Grab your bike.
No experience required.

Bike to Cure is our flagship fundraiser and annual bike ride, where 100% of participant raised dollars support cancer research at Cleveland Clinic.

The event brings together cyclist of all levels, from casual riders to seasoned professionals. Everyone is united by a common goal: to make a meaningful difference in the fight against cancer. Bike to Cure weekend includes Ride Day which features multiple route options to accommodate all levels of Riders, along with the annual Kickoff Party which celebrates the VeloSano community.

Bike to Cure is Back!

Join the Movement.

Together, we are VeloSano.
Together, to cure cancer.

Register

Make a Donation

Search for and donate to a participant or team

Search Now

Fundraising Guide

Our fundraising guide will make the process simple, fun, and rewarding – so you can focus on making a meaningful impact.

Start Fundraising

Fast Facts

View a snapshot of Bike to Cure 2025 registration details.

Fast Facts

Impact Report

Explore how VeloSano is funding lifesaving cancer research at Cleveland Clinic.

See the Impact

A route for you. And you. And you.

Guardians City Loop

A flat, urban ride that’s perfect for everyone and every bike.

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12-Mile Ride

A ride that extends the Guardians City Loop urban ride further west.

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25-Mile Ride

A mostly flat ride perfect for the casual rider.

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50-Mile Ride

Challenge yourself with this fun 50-Mile course!

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75-Mile Ride

Want to ride more than 50 miles but not quite ready to tackle the 100-mile?

Learn More

100-Mile Ride

Tackle a challenging century through Cleveland’s East side!

Learn More

Be a part of something big.

100% for the cure.

Register Today!

9500 Euclid Avenue, HS1-15

Cleveland, OH 44195

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